# 1,4bdo feels harsh? There may be a solution
**URL:** https://forum.research-community.org/t/1-4bdo-feels-harsh-there-may-be-a-solution/44
**Category:** Harm Reduction
**Tags:** alcohol, ghb, harm-reduction, l-theanine, 14bdo
**Created:** [May 20, 2023, 8:15am UTC](https://forum.research-community.org/t/1-4bdo-feels-harsh-there-may-be-a-solution/44 "2023-05-20T08:15:13Z")
**Posts on this page:** 3
**Page:** 1
### Author:  [@float](https://forum.research-community.org/u/float)
#### Post date: [May 20, 2023, 8:15am UTC](https://forum.research-community.org/t/1-4bdo-feels-harsh-there-may-be-a-solution/44/1 "2023-05-20T08:15:13Z")
Some people report _ **1,4bdo** _ being very harsh on their body, with a nasty hangover and just not a good feeling overall.
This is entirely individual first of all but there may be some science to it.
> **[Effects of theanine on alcohol metabolism and hepatic toxicity - PubMed](https://pubmed.ncbi.nlm.nih.gov/16141543/)**
>
> We previously showed that theanine, is a major amino acid in green tea, enhanced doxorubicin (DOX) induced antitumor activity. Besides, theanine induced the elevation of glutathione (GSH) level attributable to the increase of glutamate in the liver...
Take l-theanine! It seems to help your liver to correctly metabolize 1,4bdo.
Now, scientifically, it seems unusual that you have an abnormal activity of alcohol dehydrogenase. In everyone there are enough enzymes to convert BDO and GHB within an 45 mins or less.
But, if you were deficient, in any way, it’d take A LOT OF TIME for it to clear your system hence the terrible hangovers from acetaldehyde buildup / same applies to alcohol, GHB and GBL.
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### Author:  [@sash](https://forum.research-community.org/u/sash)
#### Post date: [May 20, 2023, 8:19am UTC](https://forum.research-community.org/t/1-4bdo-feels-harsh-there-may-be-a-solution/44/2 "2023-05-20T08:19:05Z")
Drink lot’s of water too. this will make you pee alot so keep hydrated!
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### Author:  [@float](https://forum.research-community.org/u/float)
#### Post date: [May 20, 2023, 9:59am UTC](https://forum.research-community.org/t/1-4bdo-feels-harsh-there-may-be-a-solution/44/3 "2023-05-20T09:59:43Z")
Completely correct!